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Dr Karthikeyan G, Chennai 06 January 2018
Parenteral anticoagulation can be overlapped with a NOAC instead of warfarin. NOACs are effective in treatment of acute VTE and prevention of recurrence in the longterm and extended-term. But remember patients with progressive DVT/PE with unstable hemodynamics still require conventionaltherapy with a heparin/fondaparinux with warfarin.
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